EU Healthcare Professionals

This is an international website for NERLYNX® dedicated to EU Healthcare professionals (outside the UK and ROI).

IMPORTANT: the information on this website is based on the European Summary of Product Characteristics. Prescribing Information and indication may vary per country. You must refer to your country prescribing information. Please be aware we do not take responsibility for accessing such information which may not comply with the regulation or usage in your country.

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I am a Healthcare Professional in the EU (outside the UK and ROI) and I have read the information above, the Legal Notice and the Privacy Policy

Patients / Non EU Healthcare Professionals

This is an international website for NERLYNX® dedicated to EU Healthcare Professionals (outside the UK and ROI)

I am a patient or a Healthcare Professional outside the EU.

https://www.pierre-fabre.com/en

heading-Nerlynx-Neratinib--HER2-Breast-Cancer

Resources

Educational Materials for diarrhoea management

According to the Risk Management Plan (RMP), educational materials are provided for you and your patients.

You can contact your Pierre Fabre local representative or our medical information to get these educational materials, which are specific to each country.

Other NERLYNX^® Support Materials

Other materials are available for you to help support your patients throughout their treatment with NERLYNX^®.

Please refer to the materials approved in your country.

Physician Tool V4 photo

Pharmacist tool V3 photo

Physician Tool - How to use NERLYNX

pdf (726.44 KB)

Pharmacist / Nurse Tool - How to use NERLYNX

pdf (907.91 KB)

Download the file

Thank you for the interest you give to our publications. Before accessing to our document, please tell us more about you.

European Summary of Product Characteristics

This is an international website for NERLYNX^®.

IMPORTANT: the information on this website is based on the European Summary of Product Characteristics. Prescribing Information and indication may vary per country. You must refer to your country prescribing information. Please be aware we do not take responsibility for accessing such information which may not comply with the regulation or usage in your country.

Pierre Fabre commitment towards breast cancer patients

Aiming to put the patient at heart of all our activities, we have created additional support tools specifically dedicated to patients, to support identified educational needs and to support them beyond the treatment.

Developed with patients, these tools are available to help your patient (or caregiver) to better understand their disease and treatment at every step.

You can ask to your Pierre Fabre representative or Medical Information if these materials are available in your country language.

My Guide to Early-Stage Breast Cancer

Beyond Hospital-Based Treatment for Early Breast Cancer: What's Next?

Download the file

Thank you for the interest you give to our publications. Before accessing to our document, please tell us more about you.

NERLYNX Patient Information Leaflet-page-001

NERLYNX Patient Information Leaflet-page-002

NERLYNX Patient Information Leaflet-page-003

NERLYNX Patient Information Leaflet-page-004

NERLYNX Patient Information Leaflet-page-005

NERLYNX Patient Information Leaflet-page-006

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NERLYNX Patient Information Leaflet-page-008

NERLYNX Patient Information Leaflet-page-009

NERLYNX Patient Information Leaflet-page-010

NERLYNX Patient Information Leaflet-page-011

Contenu de la pop in (ici, un H3)

A noter que le contenu de la pop in est prise en compte pour le SEO.

Il est donc nécessaire de bien baliser les titres. Nous conseillons d'utiliser un H2 ou un H3 (pas de H1).

This medicinal product is subject to risk minimization measures.

References
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3. Martin M, et al. Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Oncol. 2017;18(12):1688−1700.
4. Holmes FA, et al. Overall survival with neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET). European Journal of Cancer 184 (2023) 48e59.
5. Nerlynx (neratinib 40 mg film-coated tablets) Summary of Product Characteristics, 2023. Available at: https://www.ema.europa.eu/en/medicines/human/EPAR/nerlynx. Accessed: 2023.
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20. Paplomata E, et al. Systemic Therapy For Early-Stage HER2-Positive Breast Cancers: Time for a Less-Is-More Approach? Cancer. 2015;121(4):517–526.
21. Barcenas CH, et al. Improved tolerability of neratinib in patients with HER2-positive early-stage breast cancer: the CONTROL trial. Ann Oncol. 2020;31(9):1223−1230.
22. European Medicines Agency Public Assessment Report (EPAR). Nerlynx EMA/CHMP/525204/2018.
23. Barcenas CH, et al. CONTROL trial Supplementary Table S7, available at Ann Oncol online.
24. Cancer.Net. Doctor-Approved Patient Information from ASCO on Diarrhoea. Available at: https://www.cancer.net/coping-with-cancer/physical-emotional and-social-effects-cancer/managing-physical-side-effects/diarrhea. Accessed: June 2020.
25. National Cancer Institute. Diarrhoea and Cancer Treatment. Available at: https://www.cancer.gov/about-cancer/treatment/side-effects/diarrhea. Accessed: December 2022.
26. Chan A, et al. Effect of prophylaxis or neratinib dose escalation on neratinib-associated diarrhoea and tolerability in patients with HER2-positive early stage breast cancer: phase II CONTROL trial. Poster P5-14-03 presented at SABCS 2019.
27. Mortimer J, et al. Patterns of occurrence and implications of neratinib-associated diarrhoea in patients with HER2-positive breast cancer: analyses from the randomized phase III ExteNET trial. Breast Cancer Res. 2019;21(1):32. Electronic Supplementary Material.
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38. EU PAS Register, EUPAS41584. Available at: https://www.encepp.eu/encepp/viewResource.htm?id=44630. Accessed: January 2023.

This is an international website for NERLYNX^®. IMPORTANT: the information on this website is based on the European Summary of Product Characteristics. Prescribing Information and indication may vary per country. You must refer to your country prescribing information. Please be aware we do not take responsibility for accessing such information which may not comply with the regulation or usage in your country.

Last update: 09/2023